nocuous \NOK-yoo-uhs\, adjective:
very hurtful; noxious
The most important conclusions are that the bile of nocuous or venomous serpents is the most powerful antidote to venom.
-- Nature, May-October 1898
"Let us take for example a nocuous stimulus, such as a strong electric current or wounding or cauterization of the skin."
-- Ivan Petrovich Pavlov, Conditioned Reflexes
by 1627 from Latin nocuus "hurtful," from root of nocere "to injure, harm," from causative form of Proto Indo-European *nek- "death."
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